Dietary Supplements information including Melatonin

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Melatonin

Melatonin, or 5-methoxy-N-acetyltryptamine, is a hormone produced by the pineal gland, located in the center of the brain. It is a derivative of the amino acid tryptophan.

MELATONIN As recently confirmed in the news, sleepless nights can take a toll on health! Melatonin is a hormone that helps control the sleep/wake cycle. Supplementing with small amounts of this important substance may help restore normal sleep patterns while providing excellent antioxidant support.

Melatonin helps regulate sleep-wake or circadian rhythms. Normally, production of melatonin by the pineal is stimulated by darkness and inhibited by light.

In recent times, melatonin has become available as a drug and a supplement. It appears to have some use against insomnia and jet lag.

To synthesize melatonin, serotonin is converted to N-acetyl serotonin by the enzyme 5-HT N-acetyltransferase. N-acetyl serotonin is then converted to melatonin by the enzyme 5-hydroxyindole-O-methyltransferase. See serotonin for details on how tryptophan is converted to serotonin.

Consult your physician before begining any dietary supplement regimen.

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FEDERAL HEALTH ORGANIZATIONS

Food and Drug Administration (FDA)
FDA regulates dietary supplements under a different set of regulations than those covering "conventional" foods and drug products (prescription and Over-the-Counter). Under the Dietary Supplement Health and Education Act of 1994 (DSHEA), the dietary supplement manufacturer is responsible for ensuring that a dietary supplement is safe before it is marketed. FDA is responsible for taking action against any unsafe dietary supplement product after it reaches the market. Generally, manufacturers do not need to register with FDA nor get FDA approval before producing or selling dietary supplements. Manufacturers must make sure that product label information is truthful and not misleading.

United States Department of Health and Human Services
Thee United States government's principal agency for protecting the health of all Americans and providing essential human services, especially for those who are least able to help themselves.The department has more than 300 programs.

Nutrition.gov
Nutrition and health information on government websites.