Dietary Supplements information including L-Phenylalanine

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L-Phenylalanine

L-phenylalanine is a protein amino acid. It is classified as an essential amino acid because the body requires a dietary source of the amino acid to meet its physiological demands. L-phenylalanine is found in proteins of all life forms. Dietary sources of the amino acid are principally derived from animal and vegetable proteins. Vegetables and juices contain small amounts of the free amino acid. The free amino acid is also found in fermented foods such as yogurt and miso. The alternative sweetener aspartame is a dipeptide of L-phenylalanine, as is the methyl ester, and L-aspartic acid.

In addition to being involved in protein synthesis, L-phenylalanine is the precursor of L-tyrosine. The conversion of L-phenylalanine to L-tyrosine is via the enzyme L-phenylalanine hydroxylase. It is this enzyme that is virtually absent in those with the inborn error of metabolism phenylketonuria (PKU). L-tyrosine produced from L-phenylalanine is a precursor in the synthesis of the neurotransmitters norepinephrine and dopamine, among other reactions. L-phenylalanine is marketed as a nutritional supplement and used by some for its putative antidepressant activity.

Consult your physician before begining any dietary supplement regimen.

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FEDERAL HEALTH ORGANIZATIONS

Food and Drug Administration (FDA)
FDA regulates dietary supplements under a different set of regulations than those covering "conventional" foods and drug products (prescription and Over-the-Counter). Under the Dietary Supplement Health and Education Act of 1994 (DSHEA), the dietary supplement manufacturer is responsible for ensuring that a dietary supplement is safe before it is marketed. FDA is responsible for taking action against any unsafe dietary supplement product after it reaches the market. Generally, manufacturers do not need to register with FDA nor get FDA approval before producing or selling dietary supplements. Manufacturers must make sure that product label information is truthful and not misleading.

United States Department of Health and Human Services
Thee United States government's principal agency for protecting the health of all Americans and providing essential human services, especially for those who are least able to help themselves.The department has more than 300 programs.

Nutrition.gov
Nutrition and health information on government websites.